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Development Solutions and Services
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Development Solutions & Services
PI Health Sciences offers end-to-end Development Services & Solutions, specializing in complex chemistries, flow chemistry, biocatalysis, and high-potency capabilities. With advanced process R&D, multi-ton scale manufacturing, and a focus on speed, reliability, and sustainability, we partner with pharma and biotech to deliver innovative, cost-effective solutions at any scale.
Process R&D
- Phase-appropriate development
- Process optimization & validation
- GMP/non-GMP scale-up
- High potency capabilities
- Advanced chemistry expertise
- Regulatory compliance focus
Flow Chemistry
PI Health Sciences’ Center of Excellence features a cutting-edge flow chemistry setup for R&D and pilot-scale continuous manufacturing, offering process development, non-GMP, and GMP production services for projects at any stage, from pre-clinical to commercial. Our Flow Chemistry Lab includes various reactors such as Fixed Bed, Slurry Flow, MMRS (Modular Micro Reaction System), CSTR (Continuous Stirred Tank Reactor), Annular Centrifugal Extractor, Short Path Distillation Unit, and Pinched Tube reactors.
Collaborating with Flowid, we convert batch operations into optimized flow processes, enhancing efficiency and scalability. Our fully automated Flow Chemistry Pilot Plant at the Udaipur R&D center, with a 1 MT/day capacity and PLC controller, can handle hazardous reactions under high pressure and temperature. The plant is supported by a centralized LIMS system for seamless data management.
Our chemical transformation capabilities include low-temperature metallo-organic reactions, high-temperature/pressure reactions, ozonolysis, oxidation with air/oxygen or peroxides, nitrogen-rich reactions with azides or hydrazine, photochemistry, hydrogenation, and nitration.
Biocatalysis
PI Health Sciences is dedicated to “Reimagining a Healthier Planet” through biocatalysis, offering greener, cost-effective alternatives to traditional synthetic pathways. Our biocatalytic processes reduce energy consumption, minimize waste, and efficiently resolve chiral molecules. We are equipped with state-of-the-art facilities, including Fermentors, Tangential Flow Filtration Systems, and Lyophilizers. Our team of 32 scientists at the Biocatalysis lab udaipur specializes in gene/enzyme identification, microbial strain engineering, and bioconversions. Our lab is equipped with advanced analytical tools like HPLC, GC, and Next Generation Chromatography Systems. Contact us for biocatalytic reactions involving various enzymes, including Oxidoreductase, Transferase, and more.
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Our team is committed to partnering with you and supporting your goals and objectives across the pharma value chain.